Prof. Shiow-Chwen Tsai
Tsai, Shiow-Chwen, Ph.D.
Office address: 7th Floor, Administrative Building
No. 101, Zhungcheng Rd, Section 2,
Shilin District, Taipei, Taiwan 111
Phone +886-2-28718288 ext 5813
Fax +886-2- 28751116
Associate Professor, Chair of Institute of Sports Sciences
University of Taipei, Taipei, Taiwan
Ph.D. National Yang-Ming University, 1992-1997
Interdisciplinary: Endocrinology, Molecular Biology of cardiomyocyte
M.S. Yang-Ming Medical College, 1990-1992
B.A. Kaohsiung Medical College, 1985-1989
Chair, Institute of Sports Sciences (2013-present)
Assistant professor (1999-2002), Kang-Ning Junior College of Medical Care and Management
Priciple Investigator (2002-2008), Shin Kong Wu Ho-Su Memorial Hospital
Assistant professor (2008-2010), Department of Transition and Leisure Eduacation for Individuals with Disabilities
Associate professor (2010-2015), Institute of Sports Sciences
Affiliate Professor, Department of Food Science, Nutrition and Nutraceutical Biotechnology, Shih-Chien University (2009-present)
4.6 in 5.0 scale (2015), University of Taipei (student online survey)
Human Anatomy and Physiology
Exercise Physiology and Metabolism
Human Health and Aging
Local Academic Service
Secretory, Society of Adaptive Science in Taiwan (2009-2011)
- Wang PS, Tsai· SC, Hwang GS, Wang SW, Lu CC, Chen JJ, Liu SR, Lee KY, Chien EJ, Chien CH. Calcitonin inhibits testosterone and luteinizing hormone secretion through a mechanism involving an increase in cAMP production in rats. Journal of Bone and Mineral Research 1994; 9(10):1583-1590.
- Tsai SC, Chiao YC, Lu CC, Doong M, Chen YH, Shih HC, Liaw C, Wang S, Wang PS. Inhibition by amphetamine of testosterone secretion through a mechanism involving an increase of cyclic AMP production in rat testes. British Journal of Pharmacology 1996; 118(4): 984–988.
- Lu SS, Lau CP, Tung YF, Huang SW, Chen YH, Shih HC, Tsai SC, Lu CC, Wang SW, Chen JJ, Chien EJ, Chien CH, Wang PS. Lactate stimulates progesterone secretion via an increase in cAMP production in female rats. The American journal of physiology 1996; 271(5 Pt 1):E910-915.
- Tsai SC, Chen JJ, Chiao YC, Lu CC, Lin H, Yeh JY, Lo MJ, Kau MM, Wang SW, Wang PS. The role of cyclic AMP production, calcium channel activation and enzyme activities in the inhibition of testosterone secretion by amphetamine. British Journal of Pharmacology 1997; 122(5): 949–955.
- Chen TS,·Doong ML, Wang SW, Tsai SC, Lu CC, Shih HC, Chen YH, Chang FY, Lee SD, Wang PS. Gastric emptying and gastrointestinal transit during lactation in rat. The American Journal of Physiology 1997; 272(3 Pt 1):G626-631.
- Lu SS, Lau CP, Tung YF, Huang SW, Chen YH, Shih HC, Tsai SC, Lu CC, Wang SW, Chen JJ, Chien EJ, Chien CH, Wang PS. Lactate and the effects of exercise on testosterone secretion: evidence for the involvement of a cAMP-mediated mechan Tsai SC, Chen CW, Yu PL, and Wang PS. Adaptation and dysadaptation of abuse-Independent physiological responses to amphetamine. Adaptive Medicine 2014; 6 (4): 137-147.ism. Medicine and Science in Sports and Exercise 1997, 29(8):1048-1054.
- Doong ML, Lu CC, Kau MM, Tsai SC, Chiao YC Chiao, Chen JJ, Yeh JY, Lin H, Huang SW, Chen TS, Chang FY, Wang PS. Inhibition of gastric emptying and intestinal transit by amphetamine through a mechanism involving an increased secretion of CCK inmale rats. British Journal of Pharmacology 1999; 124: 11123-1130.
- Huang WJ, Yeh JY, Tsai SC, Lin H, Chiao YC, Chen JJ, Lu CC, Hwang SW, Wang SW, Chang LS, Wang PS. Regulation of testosterone secretion by prolactin in male rats. Journal of Cellular Biochemistry 1999; 74(1):111-118.
- Kau MM, Lo MJ, Tsai SC, Chen JJ, Pu HF, Chien EJ, Chang LL, Wang PS. Effects of prolactin on aldosterone secretion in rat zona glomerulosa cells. Journal of Cellular Biochemistry 1999; 72(2):286-293.
- Kau MM, Lo MJ, Tsai SC, Chen JJ, Lu CC, Lin H, Wang SW, Wang PS. Effects of estradiol on aldosterone secretion in ovariectomized rats. Journal of Cellular Biochemistry 1999; 73(1):137-144.
- Lin H, Wang SW, Tsai SC, Chen JJ, Chiao YC, Lu CC, Huang WJS, Wang GJ, Chen CF, Wang PS. Inhibitory effect of digoxin on testosterone secretion through mechanisms involving decrease of cyclic AMP production and cytochrom P450scc activity in rat testicular interstitial cells. British Journal of Pharmacology 1999; 125(8):1635-1640.
- Lu CC, Tsai SC, Huang WJS, Tsai CL, Wang PS. Effects of hyperprolactinemia on calcitonin secretion in male rats. Metabolism 1999; 48(2):221-226.
- Tsai SC, Lu CC, Chen JJ, Chiao, YC, Wang SW, Hwang, Wang PS. Inhibition of salmon calcitonin on secretion of progesterone and GnRH-stimulated pituitary luteinizing hormone. The American Journal of Physiology 1999; 277(1 Pt 1):E49-55.
- Yeh JY, Tsai SC, Kau MM, Lo MJ, Wang PS. Effects of thyroid hormones on the release of Calcitonin Gene-Related Peptide (CGRP) by rat prostate glands in vitro. The Chinese Journal of Physiology 1999; 42(2):89-94.
- Lin H, Tsai SC, Chen JJ, Chiao YC, Wang SW, Wang GJ, Chen CF, Wang PS. Effect of evodiamine on the secretion of testosterone in rat testicular interstitial cells. Metabolism 2000; 48(12-48):1532-1535.
- Lu CC, Tsai SC, Chien EJ, Tsai CL, Wang PS. Age-related differences in the secretion of calcitonin in male rats. Metabolism 2000; 49(2):253-258.
- Wang R, Tsai SC, Chen JJ, Wang PS. The simulation effects of mountain climbing training on selected endocrine responses. The Chinese Journal of Physiology 2001; 44(1):13-18
- Tsai SC, Chiao YC, Lu CC, Wang PS. Stimulation of the secretion of luteinizing hormone by ginsenoside-Rb1 in male rats. The Chinese Journal of Physiology 2003; 46(1):1-7.
- Tsai SC, Lu CC, Lin CS, Wang PS. Antisteroidogenic Actions of Hydrogen Peroxide on Rat Leydig Cells. Journal of Cellular Biochemistry 2003; 90(6):1276-1286.
- Lin SK, Tsai SC, Lee CC, Wang BW, Liou JY, Shyu KG. Berberine inhibits HIF-1α expression via enhanced proteolysis. Molecular Pharmacology 2004; 66(3):612-619
- Shyu KG, Tsai SC, Wang BW, Liu YC, Lee CC. Saikosaponin C induces endothelial cells growth, migration and capillary tube formation. Life Science 2005; 76(7):813-26.
- Lee CC, Chen SC, Tsai SC, Wang BW, Liu YC, Lee HM, Shyu KG. Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells. Journal of Biomedical Science 2006; 13(1):143-156.
- Lin WT, Yang SC, Tsai SC, Huang CC, and Lee NY. L-arginine attenuated xanthine oxidase and myeloperoxidase activities in hearts of rats during exhaustive exercise. British Journal of Nutrition 2006; 95:67-75. (SCI)
- Shyu KG, Lin S, Lee CC, Chen Eden, Lin LC, Wang BW, and Tsai SC. Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity. Life Science 2006; 78: 2234-2243. (SCI)
- Tsai SC, Liu YC, Li CP, Huang TS, and Lee CC. Sesamin inhibits vascular endothelial cell growth and angiogenic activity of lung adenocarcinoma cells. Journal of Cancer Molecule 2006; 2:199-205.
- Lu CC, and Tsai SC. The cyclic AMP-dependent protein kinase A pathway is involved in progesterone effects on calcitonin secretion from TT cells. Life Science 2007; 81:1411-1420.
- Huang CC, Tsai SC, and Lin WT. Potential ergogenic effects of l-arginine against oxidative and inflammatory stress induced by acute exercise in aging rats. Experimental Gerontology. 2008; 43:571-577.
- Chen MC, Wang SW, Kan SF, Tsai SC, Wu YC, and Wang PS. Stimulatory Effects of Propylthiouracil on Pregnenolone Production through Upregulation of Steroidogenic Acute Regulatory Protein Expression in Rat Granulosa Cells. Toxicological Science 2010; 118:667-674.
- Chou CC, Bai CH, Tsai SC, and Wu MS. Low Serum acylated ghrelin levels are associated with the development of cardiovascular disease in hemodialysis patients. Internal Medicine 2010; 49:2057-2064.
- Tsai SC, Chen CP, Su TH, Kau MM, and Lu CC. Involvement of ERK phosphorylation in the prevention of ischemia-induced ovarian follicular depletion by stem cells. Chin. J. Physiol. 2010; 53:167-177.
- Chan CC, Tsai SC, Cheng LY, Lee FY, Lin HC. Hemodynamic assessment of the development of portal-systemic collaterals in portal hypertensive rats. Digestive Diseases and Sciences 2011; 56: 417-424.
- Lu CC, and Tsai SC. Involvement of the cyclic-AMP-dependent protein kinase A pathway in thyroxine effects on calcitonin secretion from TT cells. Hormone Metabolic Research 2011; 43: 31-36.
- Wong SL, Chang HS, Wang GJ, Chiang MY, Huang HY, Chen CH, Tsai SC, Lin CH, Chen IS. Secondary metabolites from the roots of Neolitsea daibuensis and their anti-inflammatory activity. Journal of Natural Products 2011;74(12):2489-2496. Epub 2011 Dec 7.
- Kau MM, Wang JR, Tsai SC, Yu CH, Wang PS. Inhibitory effect of bufalin and cinobufagin on steroidogenesis via the activation of ERK in human adrenocortical cells. British Journal of Pharmacology 2012;165(6):1868–1876.
- Lin SJ, Tu YK, Tsai SC, Lu HK. Nonsurgical periodontal therapy with and without subgingival minocycline administration in patients with poorly controlled type II diabetes. A randomized controlled clinical trial. Clinical Oral Investigation, 2012; 16:599–609.
- 2013Tsai YL, Tsai SC, Yen SH, Huang KL, Mu PF, Liou HC, Wong TT, Lai IC, Liu P, Lou HL, Chiang IT, and Chen YW. Efficacy of therapeutic play for pediatric brain tumor patients during external beam radiotherapy. Child's Nervous System, 2013; 29(7):1123-1129.
- Tsai SC, Chen CW, Yu PL, and Wang PS. Adaptation and dysadaptation of abuse-Independent physiological responses to amphetamine. Adaptive Medicine 2014; 6 (4): 137-147.
- Lin JF, Lin YH, Liao PC, Lin YC, Tsai TF, Chou KY, Chen HE, Tsai SC, Hwang TIS. Induction of testicular damage by daily methamphetamine administration in rats. The Chinese Journal of Physiology 2014; 57(1):19-30.
- Liou CM, Tsai SC, Kuo CH, Ting H, Lee SD. Cardiac Fas-dependent and mitochondria-dependent apoptosis after chronic cocaine abuse. Internal Journal of Molecular Science, 2014;15(4), 5988-6001.
- Liou, C. M., Tsai, S. C., Kuo, C. H., Williams, T., Ting, H., & Lee, S. D. Chronic methamphetamine exposure induces cardiac fas-dependent and mitochondria-dependent apoptosis. Cardiovascular Toxicology, 2014;14(2), 134-144.
International Guest Lectures
- XIth World Congress of the International Society of Adaptive Medicine (ISAM 2015) between 27th-30th of May, 2015, Topic: The effect of vegetarian food on cardiac function of spontaneous hypertensive rats. Yonago, Japan.
- The 7th Symposium on Hypoxia Across Strait between 28th of August to 1st of September, 2015. Topic: The effect of mthionine restriction on cardiac function. Xining, Qinghai, China.